Vitemin D as Protection Against Serious Illnesses

You may prefer to skip this page which contains all of the ten articles listed below and instead click on the link to read the particular article of interst to you. You will also find the following  links  at the end of each article.

On this page are several Vitamin D articles published by the BBC News:

  1. “Vitamin D ‘can lower cancer risk”
  2. “Vitamin D ’slashes cancer risk”
  3. “Pain Linked with low Vitamin”
  4. “Low Vitamin D Heart Health Risk”
  5. “Vitamin D may help slow ageing”
  6. “A dose of vitamin D may help ward off tuberculosis, research suggests.”
  7. “Sunshine Protective against MS”
  8. “Vitamin D Key For Healthy Lungs”
  9. “Higher levels of vitamin D in the blood may lower the risk of multiple sclerosis (MS), research suggests.”
  10. “Vitamin D ‘cuts risk of diabetes’”

Vitamin D ‘can lower cancer risk’

Fish

Oily fish is a source of vitamin D

High doses of vitamin D can reduce the risk of developing some common cancers by as much as 50%, US scientists claim.

Researchers reviewed 63 old studies and found that the vitamin could reduce the chances of developing breast, ovarian and colon cancer, and others.

Experts said more research was needed to draw firm conclusions.

Charities cautiously welcomed the University of California study but warned too much vitamin D could harm the kidneys and liver.

The “natural” form of the vitamin, called D3, is normally produced in the skin after exposure to sunlight, but is also obtained from certain foods such as oily fish, margarine and meat.

The easiest and most reliable way of getting the appropriate amount [of Vitamin D] is from food and a daily supplement
Professor Cedric Garland

The research, done at the University of California in San Diego, looked at the relationship between blood levels of vitamin D and cancer risk.

Survival rates for Afro-Caribbean people with breast, colon, prostate and ovarian cancers are worse than for white people, possibly because dark skins are not as good at making vitamin D, the researchers said.

The papers reviewed, published worldwide between 1966 and 2004, included 30 investigations of colon cancer, 13 of breast cancer, 26 of prostate cancer and seven of ovarian cancer.

Scientists said analysis showed that, for at least some cancers, the vitamin D factor could not be ignored.

Taking 1,000 international units (IU) - or 25 micrograms - of the vitamin daily could lower an individual’s cancer risk by 50% in colon cancer, and by 30% in breast and ovarian cancer, they said.

‘Action needed’

The study acknowledged large doses of vitamin D should be treated with caution.

They failed to provide any mechanism for how low levels of vitamin D are actually linked to high incidence of cancer
Professor Colin Cooper

More than 2,000 IU - 50 micrograms - a day can lead to the body absorbing too much calcium, possibly damaging the liver and kidneys.

Professor Cedric Garland, who led the review study, said: “A preponderance of evidence, from the best observational studies the medical world has to offer…has led to the conclusion that public health action is needed.”

In the absence of sunshine, a beneficial level of vitamin D could be obtained from a combination of food sources and supplements, he said.

Professor Garland warned that sun exposure had its own concerns.

“Dark-skinned people, however, may need more exposure to produce adequate amounts of vitamin D, and some fair-skinned people shouldn’t try to get any vitamin D from the sun.

“The easiest and most reliable way of getting the appropriate amount is from food and a daily supplement.”

No proof

Professor Colin Cooper, of the Institute of Cancer Research, said further research was needed to provide definitive proof of the benefits of vitamin D.

But he said: “If you look at any individual study the evidence is really suggestive, rather than providing absolute proof.

“Also, they failed to provide any mechanism for how low levels of vitamin D are actually linked to high incidence of cancer.”

Dr Mark Metfield, of the Association for International Cancer Research, agreed the latest study provided no proof of the benefits of vitamin D.

“I am a bit cautious. There is no doubt there is a correlation between people who have higher levels of vitamin D in their blood and a lower risk of cancer - but it is only a correlation.”

The findings have been published in the American Journal of Public Health.

Story from BBC NEWS:
http://news.bbc.co.uk/go/pr/fr/-/2/hi/health/4563336.stm

Published: 2005/12/28 07:39:37 GMT

Vitamin D ’slashes cancer risk’

Pancreas

Pancreatic cancer can be difficult to treat

Taking vitamin D tablets could substantially reduce the risk of pancreatic cancer, research suggests.

US scientists found taking the tablets cut the risk of a disease, which has a poor prognosis in almost half of cases.

There are more than 3,600 new cases of pancreatic cancer in women and more than 3,500 in men in the UK each year. Surgery is not often effective.

Vitamin D was examined as it previously showed promise in cutting the risk of prostate, breast and colon cancer.

The results of this study don’t mean that people should take vitamin D supplements to ward off pancreatic cancer
Henry Scowcroft

Except for smoking, no environmental factors or dietary factors have been linked to the pancreatic cancer.

But previous studies have suggested that vitamin D might help to block the proliferation of cancer cells.

And pancreas tissue - both normal and cancerous - has been found to contain high levels of an enzyme that converts vitamin D into its active form.

Big study

For the new study, which was led by Northwestern University in Illinois and features in Cancer Epidemiology Biomarkers & Prevention, researchers examined data on more than 120,000 people from two large, long-term health surveys.

Taking the US Recommended Daily Allowance (RDA) of vitamin D (400 IU/day) was found to reduce the risk of pancreatic cancer by 43%.

They said further work was necessary to determine if consuming vitamin D in the diet, or through sun exposure might have even more of an effect than taking supplements.

Vitamin D helps the body to form and maintain strong bones by encouraging the body to absorb calcium.

However, the researchers found no evidence of a link between risk of the cancer and calcium, or retinol, a vitamin which affects vitamin D’s impact on calcium absorption.

Multi-vitamin supplements, often contain retinol.

Lead researcher Dr Hal Skinner said: “There is a growing body of information indicating that achieving higher levels of vitamin D through supplements, diet or prudent sun exposure may provide a range health benefits by preventing common chronic diseases.”

More work needed

He said certain groups could be defined as being at higher risk for pancreatic cancer - for example cigarette smokers or those with a family history of the disease.

However, he said: “I would make no specific recommendation for vitamin D supplementation to prevent pancreatic cancer until we can carry out a trial to determine definitively who might benefit from such an intervention.”

Henry Scowcroft, science information officer at the charity Cancer Research UK, said: “The results of this study don’t mean that people should take vitamin D supplements to ward off pancreatic cancer, especially as vitamin D can be harmful in large quantities.

“As the authors themselves point out, this is the very first study to find any association between the disease and vitamin D intake.

“So this result needs to be repeated in other large studies, and scientists need to show exactly how vitamin D might prevent pancreatic cancer before we could issue any specific lifestyle advice.”

Story from BBC NEWS:
http://news.bbc.co.uk/go/pr/fr/-/2/hi/health/5334534.stm

Published: 2006/09/15 23:17:45 GMT

Pain ‘linked with low vitamin D’

x-ray showing osteomalacia

Severe vitamin D deficiency leads to osteomalacia

Low levels of the sunshine vitamin, vitamin D, may contribute to chronic pain among women, scientists believe.

The link does not apply to men, suggesting hormones may be involved, according to a study published in the Annals of Rheumatic Diseases said.

The team from the Institute of Child Health in London said studies were now needed to see if vitamin D supplements can guard against chronic pain.

About one in 10 people are affected by chronic pain at any one time in the UK.

The causes are not well understood and much of the focus to date has been on emotional factors.

Dr Elina Hyppönen and colleagues believe, at least in women, vitamin D levels could play a role in some cases of chronic pain.

Sunshine vitamin

The nutrient, essential for healthy bones, is produced in the body when exposed to sunlight and is also found in oily fish, egg yolks and margarine.

Among the 7,000 men and women aged 45 from across England, Scotland and Wales that they studied, those who were smokers, non-drinkers, the overweight and the underweight all reported higher rates of chronic pain.

Among the women, vitamin D levels also appeared to be important.

This finding was not explained by gender differences in lifestyle or social factors, such as levels of physical activity and time spent outdoors, say the authors.

Women with vitamin D levels between 75 and 99 mmol/litre - a level deemed necessary for bone health - had the lowest rates of this type of pain, at just over 8%.

Women with levels of less than 25 mmol/litre had the highest rates, at 14.4%.

Severe lack of vitamin D in adults can lead to the painful bone disease osteomalacia.

But the researchers said osteomalacia did not account for their findings.

Dr Hyppönen said work was needed to evaluate whether vitamin D supplements could help prevent chronic pain.

In the meantime, she advised: “If I had chronic pain I would certainly check I was getting enough vitamin D.”

Kate MacIver of the Pain Research Institute at Liverpool University cautioned: “Taking too high a dose of Vitamin D supplements as a means of preventing or treating chronic pain could result in Vitamin D toxicity and high blood calcium levels.”

Most people should be able to get all the vitamin D they need from their diet and by getting a little sun.

However, if you are pregnant or breastfeeding you should take 10 micrograms (0.01 mg) of vitamin D each day, the Food Standards Agency recommends.

Older people should also consider taking 10 micrograms (0.01 mg) of vitamin D each day.

Story from BBC NEWS:
http://news.bbc.co.uk/go/pr/fr/-/2/hi/health/7553833.stm

Published: 2008/08/11 23:34:16 GMT

Low vitamin D heart health risk

Sun

The sun is a key source of vitamin D

Having too little vitamin D has been linked to an increased risk of heart disease, a US study has found.

The Harvard Medical School team said the risk was particularly high for those who also had high blood pressure.

Writing in the journal Circulation, they said correcting vitamin D deficiency could be beneficial.

A British Heart Foundation spokeswoman said more information was needed on how the vitamin affected heart health.

Blood pressure link

Vitamin D is mainly obtained from exposure to the sun, as well as from certain foods such as oily fish and eggs.

There are concerns that many people, including the elderly, pregnant women and those who wear all-concealing clothing do not get enough of the vitamin.

A lack of the nutrient, already known to cause weakened bones, has also been linked to multiple sclerosis and rheumatoid arthritis.

Vitamins are easy to administer and in general have few toxic effects
Dr Thomas Wang, Harvard Medical School

The US study, which began in 1996, looked at over 1,700 people with an average age of 59.

Their vitamin D levels were tested and they were then monitored for up to seven years.

Those with low levels of vitamin D in their blood, below 15 nanograms per millilitre (ng/ml), had twice the risk of a heart attack, heart failure or a stroke compared to those with higher levels (above 15ng/ml).

The highest incidence of cardiovascular disease was seen in those with high blood pressure and low vitamin D levels.

Overall, 28% of individuals had levels of vitamin D below 15 ng/ml. Only 10% had levels above 30 ng/ml - considered ideal for bone health.

The researchers say that because receptors for vitamin D are found in heart muscle and blood vessel lining, low levels could be a contributing factor in heart disease.

Uncertainty

But Dr Thomas Wang, who led the research, added: “What hasn’t been proven yet is that vitamin D deficiency actually causes increased risk of cardiovascular disease.

“This would require a large randomised trial to show whether correcting the vitamin D deficiency would result in a reduction in cardiovascular risk.”

Other studies looking at using different vitamins to benefit heart health have not shown positive results.

But Dr Wang said: “Just because other vitamins haven’t succeeded doesn’t preclude the possibility of finding vitamins that might prevent cardiovascular disease.

“Vitamins are easy to administer and in general have few toxic effects.”

June Davison, cardiac nurse at the British Heart Foundation said: “This study suggests an association with Vitamin D deficiency and an increased risk of heart and circulatory disease.

“However, the reasons as to why this happens are uncertain and further research is needed to understand the mechanisms behind this.”

Story from BBC NEWS:
http://news.bbc.co.uk/go/pr/fr/-/2/hi/health/7175400.stm

Published: 2008/01/08 07:41:27 GMT

Vitamin D ‘may help slow ageing’

Vitamin D crystals

Vitamin D may have far-reaching effects in the body

A vitamin made when sunlight hits the skin could help slow down the ageing of cells and tissues, say researchers.

A King’s College London study of more than 2,000 women found those with higher vitamin D levels showed fewer ageing-related changes in their DNA.

However, the American Journal of Clinical Nutrition study stops short of proving cause and effect.

A lack of vitamin D, also found in some foods, has also been linked to multiple sclerosis and rheumatoid arthritis.

It’s possible that the same sunshine which may increase our risk of skin cancer may also have a healthy effect on the ageing process in general
Professor Tim Spector
King’s College London

The genetic material inside every cell has an inbuilt “clock”, which counts down every time the cell reproduces itself.

The shortening of these strands of DNA called telomeres is one way of examining the ageing process at a cellular level.

Snapshot measurement

The King’s team looked at white blood cells, which tend to experience faster rates of turnover - and faster shortening of telomeres - when the body’s tissues are suffering more inflammation.

They looked at a total of 2,160 women aged between 18 and 79, and took a snapshot measurement of the levels of vitamin D in their bloodstream, comparing this to the length of the telomeres in their white blood cells.

They found that, after adjusting the results for the age of the volunteer, women with higher levels of vitamin D were more likely to have longer telomeres in these cells, and vice versa.

What we do know is that while telomere length can be used as a biological marker, for an individual, it is not a very precise one
Professor Thomas von Zglinicki
Newcastle University

Professor Brent Richards, who led the study, said: “These results are exciting because they demonstrate for the first time that people who have higher levels of vitamin D may age more slowly than people with lower levels of vitamin D.

“This could help to explain how vitamin D has a protective effect on many ageing-related diseases, such as heart disease and cancer.”

Another of the study’s authors, Professor Tim Spector, said: “Although it might sound absurd, it’s possible that the same sunshine which may increase our risk of skin cancer may also have a healthy effect on the ageing process in general.”

No proof

The study authors, however, conceded that while this suggested a link between vitamin D levels and telomere length, it did not provide unequivocal evidence that vitamin D was responsible for this effect, rather than some other factor unaccounted for in the research,.

Professor Thomas von Zglinicki, a leading telomere researcher from the University of Newcastle, said that this was more evidence that telomere length could be related to ageing and age-related diseases.

However, he said: “What we do know is that while telomere length can be used as a biological marker, for an individual, it is not a very precise one.

“Other studies have found that people who die at the same age can have significant differences in their telomere length - up to 30 times the differences described in this study.

“We just still don’t know how all the different factors that correlate to telomere length work together.”

He said that it was possible that vitamin D might not be delaying the shortening of telomeres, but that another factor which did this might alter the way the vitamin was created and metabolised by the body.

Story from BBC NEWS:
http://news.bbc.co.uk/go/pr/fr/-/2/hi/health/7083323.stm

Published: 2007/11/08 05:10:10 GMT

Vitamin D ‘may help ward off TB’

TB

TB rates have been rising in England, Wales and Northern Ireland

A dose of vitamin D may help ward off tuberculosis, research suggests.

A study of 131 people found the vitamin helped to boost the ability of the body to inhibit the growth of bacteria that causes the respiratory disease.

Researchers from Queen Mary’s School of Medicine and Imperial College said it could be used to target at-risk patients or added to drinks.

The study appeared in the American Journal of Respiratory and Critical Care Medicine.

Vitamin D was originally used to treat TB in sanatoriums before antibiotics came in to use.

What makes this potentially a very good intervention is that it is cheap and easy to administer
Professor Peter Davies, a chest specialist

But until now no study has evaluated the effect of vitamin D on the body’s immunity to mycobacteria, the family of bacteria that cause TB.

During the study, blood was taken from all the participants and infected with mycobacteria.

The group was then split into two with 64 given a dummy pill and the rest a 2.5mg dose of vitamin D.

After six weeks, blood was taken again and infected with mycobacteria.

The samples of blood were analysed after 24 hours, and the growth of the samples taken from people given vitamin D was 20% less than the placebo group.

The researchers said clinical trials were now needed to fully prove the findings, but they added the vitamin had the potential to help ward off the respiratory disease.

They said it could be given to those deemed at risk - the bacteria can lie dormant waiting for the immune system to be weakened before striking - or added to drinks such as milk and orange juice.

Rise

It comes as TB rose by 2% last year to over 8,000 new cases in England, Wales and Northern Ireland.

London accounted for nearly half of the cases, with the migrant population identified as the primary source.

TB is also a major global problem, responsible for 2m deaths a year.

Lead researcher Dr Adrian Martineau added: “This shows that a simple, cheap supplement could make a significant impact on the health of people most at risk from the disease.”

Professor Peter Davies, a chest specialist and secretary of the TB Alert campaign group, said: “We have known for a while vitamin D could help and it is good to see it being confirmed in such a study.

“What makes this potentially a very good intervention is that it is cheap and easy to administer. But we need to await the clinical trials.”

The results add to a growing body of evidence about the health benefits of vitamin D - it has also been linked to reducing the risk of cancer and diabetes as well as strengthening the bones.

Vitamin D ‘cuts risk of diabetes’

Giving young children vitamin D supplements may reduce their risk of developing type 1 diabetes later in life, research suggests.

Children who took supplements were around 30% less likely to develop the condition than those who did not.

Type 1 diabetes results from the immune system destruction of pancreatic cells which produce the hormone insulin.

The study, by St Mary’s Hospital for Women and Children, Manchester, appears in Archives of Disease in Childhood.

Type 1 diabetes is most common among people of European descent, with around two million Europeans and North Americans affected.

It is becoming increasingly common, and it is estimated that the number of new cases will rise by 40% between 2000 and 2010.

The Manchester team pooled data from five studies examining the effect of vitamin D supplementation.

Not only did the use of supplements appear to reduce the risk, the effect was dose dependent - the higher and more regular the dose, the lower the likelihood of developing the disease.

Sun exposure

Previous research has found that people newly diagnosed with type 1 diabetes have lower concentrations of vitamin D than those without the condition.

Studies have also found that type 1 diabetes is more common in countries where exposure to sunlight - which enables the body to manufacture vitamin D - is lower.

For instance, a child in Finland was 400 times more likely to develop the disease than a child in Venezuela.

Separate research has linked low levels of vitamin D and sunlight to other autoimmune disorders, including multiple sclerosis and rheumatoid arthritis.

Further evidence of vitamin D’s role comes from the fact that pancreatic beta cells and immune cells carry receptors or docking bays for the active forms of the vitamin.

It is thought that vitamin D helps to keep the immune system healthy, and may protect cells from damage caused by chemicals which control inflammation.

Dr Victoria King, of the charity Diabetes UK, said: “Much more research, in particular controlled trials which compares the results when one group of people are given vitamin D supplements and one group is not, are needed before we can confirm a concrete association between vitamin D and type 1 diabetes.”

Governnment experts recommend vitamin D supplementation for at least the first two years of a child’s life, although the Chief Medical Officer for England has suggested supplements for the first five years is a good idea.

Story from BBC NEWS:
http://news.bbc.co.uk/go/pr/fr/-/2/hi/health/7290423.stm

Published: 2008/03/13 00:01:21 GMT
© BBC MMVIII

Last Updated: Saturday, 28 July 2007, 23:40 GMT 00:40 UK

Sunshine ‘protective’ against MS

beach life

Some sun can be a good thing

People who spend more time in the sun as children subsequently have a lower risk of developing multiple sclerosis (MS), a US study shows.

The University of Southern California team suggest UV rays offer protection by altering the cell immune responses or by boosting vitamin D levels. An earlier study found women who took vitamin D supplements were 40% less likely to develop MS.The latest research is published in the journal Neurology.

Protective effect

MS is among the most common neurological diseases affecting around two million people worldwide.

However, it is more common at higher latitudes, which generally have lower levels of ultraviolet radiation - the type produced by the sun.

People in these countries are exposed to less sunlight, which triggers a chemical reaction in the body leading to vitamin D production.

For the study, researchers surveyed 79 pairs of identical twins who had the same genetic risk of MS.

In each pair, one of the twins had MS.

The researchers are certainly not suggesting people go out and get skin cancer. Exposure to the sun’s rays can be dangerous
Chris Jones, chief executive of the MS Trust

The twins were asked to specify whether they or their twin spent more time outdoors during hot days, cold days, and summer, and which one spent more time basking in the sun, going to the beach and playing team sports as a child.

The researchers found the twin with MS spent less time in the sun as a child than the twin who did not have MS.

Depending on the activity, the twin who spent more hours outdoors had up to a 57% reduced risk of developing MS.

The study authors, Dr Talat Islam and Dr Thomas Mack, said more work into how sun exposure reduces MS risk was now needed.

They suggested: “Exposure to ultra violet rays may induce protection against MS by alternative mechanisms, either directly by altering the cellular immune response or indirectly by producing immunoactive vitamin D.”

Chris Jones, chief executive of the MS Trust, said: “This work supports past work suggesting a link between sun exposure and a lower risk of MS.

“But the researchers are certainly not suggesting people go out and get skin cancer. Exposure to the sun’s rays can be dangerous.”

Story from BBC NEWS:
http://news.bbc.co.uk/go/pr/fr/-/2/hi/health/6906712.stm

Published: 2007/07/28 23:40:16 GMT

Vitamin D ‘key for healthy lungs’

Lung patient

Vitamin D is essential for the processing of calcium

Vitamin D could play a role in keeping the lungs healthy, research suggests. Patients with higher vitamin D levels in their blood had significantly better lung function, a University of Auckland team found in a study of 14,091 people.

The difference between the two was more marked than that between smokers and those who had quit, the study published in the journal Chest said.

Dietary supplements could boost lung function, the team suggested, but they added that more research was needed.

Chronic lung conditions compromise quality of life for millions of people around the world
Dr Michael Alberts

“Low levels of vitamin D have been associated with osteoporosis, hypertension, diabetes, and cancer,” said lead researcher Dr Peter Black.

“Our research shows that vitamin D may also have a strong influence on lung health, with greater levels of vitamin D associated with greater and more positive effects on lung function.”

Dr Black said the difference in performance between those with the highest and lowest concentrations of vitamin D was more marked that the difference between non-smokers and those who had given up.

The team found that those people with the highest concentration of vitamin D in their blood significantly outperformed others in tests to measure their lung function.

However, he said: “Although there is a definite relationship between lung function and vitamin D, it is unclear if increases in vitamin D through supplements or dietary intake will actually improve lung function in patients with chronic respiratory diseases.”

The tests included:

  • The FEV1 test which measures the volume of air that can be forced in one second after taking a deep breath.
  • The FVC test which measures the total volume of air that is expelled after taking a deep breath

The researchers found vitamin D was higher in men than women, was inversely related to obesity levels, and declined with age.

It was also lower in participants smoking more than 20 cigarettes a day compared with non-smokers.

Dr Peter Black said he was not sure why vitamin D has this effect on lung function.

But he suggested it may be because vitamin D affects the repair and remodelling of lung tissue, which goes on throughout life.

“The effects of vitamin D are not limited to bone and there is evidence that it can affect the growth of a wide variety of cell types.”

Rib cage?

Dr Mark Britton, a spokesman for the British Lung Foundation, told the BBC News website that it was likely that vitamin D had an impact on the development of the rib cage, rather than the lung tissue itself.

He said that failure to develop strong bones could impact on the size of the lungs.

Dr Michael Alberts, president of the American College of Chest Physicians, said: “Chronic lung conditions compromise quality of life for millions of people around the world.

“By understanding the effect that vitamins have on lung function, we may be able to identify new and more effective treatments for these debilitating diseases.”

Vitamin D is essential for the processing of calcium.

Unlike other vitamins, it can be made in our bodies as a result of exposure to sunlight, providing the necessary starting materials are there to start with.

It is also contained in a few foods including oily fish, fish oils, butter and eggs.

Story from BBC NEWS:
http://news.bbc.co.uk/go/pr/fr/-/2/hi/health/4521060.stm

Published: 2005/12/17 23:12:36 GMT

High vitamin D levels cut MS risk

Physiotherapy for multiple sclerosis

Vitamin D may curb the activity of rogue cells

Higher levels of vitamin D in the blood may lower the risk of multiple sclerosis (MS), research suggests.

Previous studies have suggested vitamin D may have a protective effect - but the evidence has been inconclusive.

A Harvard School of Public Health team measured levels of the vitamin in large numbers of US military personnel.

The study, published in the Journal of the American Medical Association, found the risk of MS fell as blood levels of the vitamin rose.

If confirmed, this finding suggests that many cases of MS could be prevented by increasing vitamin D levels

Dr Alberto Ascherio

Harvard School of Public Health

MS is among the most common neurological diseases affecting around two million people worldwide.

The researchers uncovered 257 cases of MS among more than seven million military personnel who had given blood samples to the US Department of Defense.

They found that among white personnel, there was a 41% decrease in MS risk for every 50 nanomoles per litre increase in 25-hydroxyvitamin D, a form of the vitamin found in the blood.

Those whose vitamin level was in the top 20% had a 62% lower risk of MS than those whose level was in the bottom 20%.

The researchers found no such association among black and hispanic personnel, but said this could be down to the smaller size of these sample groups .

Writing in the journal, the researchers said more evidence was needed before doctors suggested taking vitamin D supplements to ward off MS.

Sun factor

But lead researcher Dr Alberto Ascherio said: “If confirmed, this finding suggests that many cases of MS could be prevented by increasing vitamin D levels.

“The results of this study converge with a growing body of experimental evidence supporting the importance of vitamin D in regulating the immune system and suppressing auto-immune reactions, which are thought by most experts to play a key role in the development of MS.”

Scientists formulated the theory that vitamin D plays a significant role in protecting against MS after data which suggested the condition was more common in countries furthest from the equator.

The problem is, still, that we don’t know the nature of the picture we’re trying to build, nor how many pieces are missing

Chris Jones

MS Trust

People in these countries are exposed to less sunlight, which triggers a chemical reaction in the body leading to vitamin D production.

Previous research has shown that vitamin D supplements can prevent or favourably affect the course of a disease similar to MS in mice.

And the Harvard team has published a study which found that women who take vitamin D supplements are 40% less likely to develop MS.

MS is thought to be an auto-immune disease caused by specialised T helper 1 cells attacking myelin - the insulatory material which sheathes the nerves.

There is evidence that vitamin D reduces the activity of these rogue cells.

Jigsaw pieces

Chris Jones, chief executive of the MS Trust, said: “There is growing evidence here of a relationship between vitamin D and the risk of developing MS which provides yet another piece of the jigsaw of MS.

“The problem is, still, that we don’t know the nature of the picture we’re trying to build, nor how many pieces are missing.

“Yet these are tantalising clues, along with other recent research in the area showing that a birth month of May gives lower risk of MS than November, possibly reflecting the mother’s exposure to sunlight - which promotes the body’s production of vitamin D - during pregnancy.”

A spokesman for the MS Society agreed the results were interesting, and suggested that vitamin D levels might be a factor in predicting whether someone is more likely to develop MS.

However, he said: “Further work is needed to confirm if that is so. In the meantime, we underline the researchers’ caution that vitamin D supplements should not be used for MS prevention until and unless they are proved effective.”

Story from BBC NEWS:
http://news.bbc.co.uk/go/pr/fr/-/2/hi/health/6191131.stm

Published: 2006/12/20 00:05:53 GMT

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Read more:

Vitamin D is Not Just For the Bones

Sources of Vitamin D

Groups At Risk For Vitamin D Deficiency

Vitamin D Intake And Status

Vitamin D Deficiency

Vitamin D and Health

Health Risks from Excessive Vitamin D

Interactions with Medications

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